Preface: Modern Heterocycle Synthesis and Functionalization

Efficient Pd-catalyzed amination reactions for heterocycle functionalization.

The Pd-catalyzed amination of unprotected benzo-fused heterocycles is reported, which allows for greater flexibility and efficiency in the modification of this important class of molecules. The generality of these simple and efficient procedures is demonstrated through the synthesis of a wide variety of structural types.

Preface 1. the Modern Research Environment

The 21st century has presented the professional researcher with a myriad of challenges and opportunities. In particular, there are a number of new and exciting digital technologies, which offer researchers considerable advantages in terms of speed, access connectivity, and economy. Skype and other Voice Over Internet Protocol (VOIP) applications allow practitioners to carry out face-to-face int...

Synthesis and antitubercular activity of heterocycle substituted diphenyl ether derivatives.

Despite being an ancient disease, tuberculosis (TB) remains the leading single-agent infectious disease killer in the world. The emerging serious problem of TB control and clinical management prompted us to synthesize a novel series of heterocyclic substituted diphenyl ether derivatives and determine their activity against the H37Rv strain of Mycobacterium. All ten compounds inhibited the growt...

Pd-mediated synthesis of substituted benzenes fused with carbocycle/heterocycle.

A new Pd-catalyzed one-pot multicomponent coupling reaction for the construction of benzene ring fused with carbocycle or heterocycle under a Cu-free condition is described.

PREFACE